RESUMO: O hamartoma lipomatoso intracraniano é considerado uma lesão benigna não invasiva formada por adipócitos bem diferenciados com ou sem cápsulas. A necropsia de uma ovelha com apatia, hipocinesia, anorexia e adipsia revelou um nódulo pendular oval, macio, esbranquiçado, de aproximadamente 6 mm de comprimento na região do bulbo, localizado no pontocerebelo. A histopatologia revelou lesão proliferativa formada principalmente por adipócitos bem diferenciados, fibrócitos, fibras nervosas mielinizadas e músculo estriado esquelético caracterizando hamartoma lipomatoso intracraniano. Este é o primeiro relato da condição em ovelhas.

ABSTRACT: Intracranial lipomatous hamartomas are considered a non-invasive, benign lesion formed by well-differentiated adipocytes with or without capsules. A necropsy of an ewe presenting apathy, hypokinesis, anorexia, and adipsia revealed a soft, whitish, oval, pendular nodule approximately 6 mm long in the bulb region, located in the pontocerebellum. Histopathological assessments revealed a benign lesion formed mainly by well-differentiated adipocytes, fibrocytes, myelinated nervous fibers, and skeletal striated muscle, characterizing an intracranial lipomatous hamartoma. This is the first report of this condition in sheep.

O objetivo do presente trabalho foi determinar o proteinograma do líquido sinovial de quarenta equinos hígidos. Após colheita, centrifugação e fracionamento das amostras, as proteínas de fase aguda foram separadas por eletroforese em gel de poliacrilamida, contendo SDS-PAGE, e suas concentrações determinadas por densitometria computadorizada. Foram encontradas 16 a 26 proteínas no fracionamento eletroforético, compeso molecular variando de 16 a 238.000 Daltons (Da). Os pesos moleculares encontrados, correspondentes às proteínas mais conhecidas, foram albumina, 63.000Da; ceruloplasmina, 113.000Da; transferrina, 80.000Da; haptoglobina, 40.000Da; α-1-glicoproteínaácida, 37.000Da; IgA, 189.000Da e IgG, 74.000Da. O estabelecimento do proteinograma do líquido sinovial de equinos hígidos pode trazer contribuição significativa ao diagnóstico, tratamento e prognóstico de animais com alterações articulares.

The aim of this study was to determine the proteinogram of the proteins included in the synovial fluid of forty healthy horses. After collection, centrifugation and fractionation of the samples, the acute phase proteins were separated by electrophoresis in polyacrylamide gel containing SDS-PAGE, and their concentrations were determined by computerized densitometry. It was found 16 to 26 proteins on the electrophoretic fraction, with molecular weights from 16 to 238.000 Daltons (Da). The molecular weights found, corresponding to most known proteins were albumin, 63,000Da; ceruloplasmin, 113.000Da; transferrin, 80,000Da; haptoglobin, 40.000Da, α-1-acid glycoprotein, 37.000Da; IgA, IgG and 189.000Da, 74.000Da. The knowledge proteinogram of synovial fluid of healthy horses can bring significant contribution to the diagnosis, treatment and prognosis of animals with articular changes.

We report three cases of stings by Africanized bees in cattle in the state of Rio de Janeiro, Brazil. Erythema, subcutaneous edema, necrosis accompanied by skin detachment, and subsequent skin regeneration were observed, especially on the head and dewlap. Histopathological examinations performed 45 days later revealed complete skin reepithelialization with moderate dermal fibrosis. The clinical picture and differential diagnosis are discussed in the present manuscript, with a focus on photosensitization, which causes cutaneous lesions on the head (sequela) with cicatricial curving of the ears and can be very similar to what is observed in cattle attacked by swarms of bees. The distinction between photosensitization and bee sting lesions can be made with a focus on history and clinical and pathological aspects.